miRNA General Information
miRNA Mature ID hsa-miR-301b-3p
miRNA Stemloop AC MI0005568
miRNA Stemloop ID hsa-mir-301b
Sequence cagugcaaugauauugucaaagc
TTD Target(s) Regulated by This miRNA Mineralocorticoid receptor (MR) Successful Target Target Info [1]
DNA [cytosine-5]-methyltransferase 1 (DNMT1) Clinical trial Target Target Info [2]
Phosphatase and tensin homolog (PTEN) Literature-reported Target Target Info [3]
Protein(s) Regulated by This miRNA Bcl-2-like protein 11 Regulated Protein [4]
Tumor protein 63 Regulated Protein [5]
References
REF 1 A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2. Cancer Res. 2016 Jul 1;76(13):3838-50.
REF 2 MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes. Hepatology. 2010 Mar;51(3):881-90.
REF 3 The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN. Sci Rep. 2016 Feb 3;6:20574.
REF 4 Hypoxia-induced microRNA-301b regulates apoptosis by targeting Bim in lung cancer.Cell Prolif. 2016 Aug;49(4):476-83.
REF 5 MicroRNA-301b promotes cell invasiveness through targeting TP63 in pancreatic carcinoma cells.Int J Oncol. 2014 Mar;44(3):725-34.

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