miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-19b-1-5p | ||||
miRNA Stemloop AC | MI0000074 | ||||
miRNA Stemloop ID | hsa-mir-19b-1 | ||||
Sequence | aguuuugcagguuugcauccagc | ||||
TTD Target(s) Regulated by This miRNA | Fibroblast growth factor receptor 2 (FGFR2) | Successful Target | Target Info | [1] | |
Vascular endothelial growth factor receptor 2 (KDR) | Successful Target | Target Info | [1] | ||
G1/S-specific cyclin-D1 (CCND1) | Clinical trial Target | Target Info | [1] | ||
Caspase-8 (CASP8) | Patented-recorded Target | Target Info | [1] | ||
Proto-oncogene c-Myc (MYC) | Literature-reported Target | Target Info | [2] | ||
Integrin beta-8 (ITGB8) | Clinical trial Target | Target Info | [1] | ||
References | |||||
REF 1 | MiR-19b-1 inhibits angiogenesis by blocking cell cycle progression of endothelial cells. Biochem Biophys Res Commun. 2012 Jan 13;417(2):771-6. | ||||
REF 2 | Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma - reasons and consequences. Genes Cancer. 2014 Apr;5(1-2):56-63. |
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