miRNA General Information
miRNA Mature ID hsa-miR-15b-3p
miRNA Stemloop AC MI0000438
miRNA Stemloop ID hsa-mir-15b
Sequence cgaaucauuauuugcugcucua
TTD Target(s) Regulated by This miRNA Insulin-like growth factor I receptor (IGF1R) Successful Target Target Info [1]
Cyclin D (CCND3) Literature-reported Target Target Info [2]
Suppressor of tumorigenicity 15 protein (ST15) Literature-reported Target Target Info [3]
Protein(s) Regulated by This miRNA E3 ubiquitin-protein ligase TRIM31 Regulated Protein [4]
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Regulated Protein [5]
References
REF 1 miR-15b Inhibits the Progression of Glioblastoma Cells Through Targeting Insulin-like Growth Factor Receptor 1. Horm Cancer. 2017 Feb;8(1):49-57.
REF 2 Up-regulation of microRNA-15b correlates with unfavorable prognosis and malignant progression of human glioma. Int J Clin Exp Pathol. 2015 May 1;8(5):4943-52.
REF 3 MicroRNA-15b regulates reversion-inducing cysteine-rich protein with Kazal motifs (RECK) expression in human uterine leiomyoma. Reprod Biol Endocrinol. 2016 Aug 17;14(1):45.
REF 4 MicroRNA-15b Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF125.J Immunol. 2015 Sep 1;195(5):2251-62.
REF 5 MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4.Aging (Albany NY). 2016 Mar;8(3):484-505.

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