Target's General Information
Target ID T96916
Target Name Dickkopf-related protein 3 (DKK3)
Synonyms hDkk-3; UNQ258/PRO295; REIC; Dkk-3; Dickkopf-3
Target Type Clinical trial
Gene Name DKK3
Biochemical Class Dickkopf protein
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Prostate cancer
Example drug REIC gene therapy Phase 1/2 [1], [2], [3]
Tissue Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.81
Z-score: 1.19
P-value: 4.23E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
REF 1 (NCT01931046) Study of a Recombinant Adenovirus to Treat Localized Prostate Cancer. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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