Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T94482 | ||||
| Target Name | Interleukin-20 (IL20) | ||||
| Synonyms | ZCYTO10; UNQ852/PRO1801; IL-20; Four alpha helix cytokine ZCYTO10; Cytokine Zcyto10 | ||||
| Target Type | Clinical trial | ||||
| Gene Name | IL20 | ||||
| Biochemical Class | Cytokine: interleukin | ||||
| UniProt ID | IL20_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Psoriasis | ||||
| Example drug | NN-8226 | Phase 2 | [1], [2] | ||
| Tissue | Skin | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 1.01 Z-score: 1.18 P-value: 1.82E-12 |
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| Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section |
Fold-change: 1.79 Z-score: 7.42 P-value: 3.31E-85 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
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| References | |||||
| REF 1 | ClinicalTrials.gov (NCT02097264) A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate. U.S. National Institutes of Health. | ||||
| REF 2 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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