Target's General Information
Target ID T91286
Target Name Metalloreductase STEAP1 (STEAP1)
Synonyms Sixtransmembrane epithelial antigen of prostate 1; STEAP1
Target Type Clinical trial
Gene Name STEAP1
Biochemical Class Metal ion oxidoreductase
UniProt ID STEA1_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Prostate cancer
Example drug RG7450 Phase 1 [1], [2], [3]
Tissue Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.78
Z-score: 1.22
P-value: 1.46E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033873)
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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