Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T85857 | ||||
| Target Name | Thymic stromal lymphopoietin (TSLP) | ||||
| Synonyms | Thymic stromal lymphopoietin | ||||
| Target Type | Successful | ||||
| Gene Name | TSLP | ||||
| UniProt ID | TSLP_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Asthma | ||||
| Example drug | MEDI9929 | Phase 2 | [1], [2] | ||
| Tissue | Nasal and bronchial airway | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.3 Z-score: 0.26 P-value: 8.89E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| References | |||||
| REF 1 | ClinicalTrials.gov (NCT02054130) Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma. U.S. National Institutes of Health. | ||||
| REF 2 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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