| Target's General Information |
| Target ID |
T58970 |
| Target Name |
Extracellular signal-regulated kinase 2 (ERK2) |
| Synonyms |
PRKM2; PRKM1; P42-MAPK; P42 Mitogen-activated protein kinase; Mitogen-activated protein kinase 2; Mitogen-activated protein kinase 1; MAPK 2; MAPK 1; MAP kinase isoform p42; MAP kinase 2; MAP kinase 1; ERT1; ERK-2 |
| Target Type |
Clinical trial |
| Gene Name |
MAPK1 |
| Biochemical Class |
Kinase |
| UniProt ID |
MK01_HUMAN |
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People |
| Disease |
Rheumatoid arthritis |
| Tissue |
Synovial tissue |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 1.12
Z-score: 2.73
P-value: 6.78E-05
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| Target's Expression Profile across Various Tissues of Healthy Individual |
|
| References |
| REF 1 |
Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
|
| REF 2 |
NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.
|
