Target expression details
Target's General Information | |||||
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Target ID | T58920 | ||||
Target Name | Thyrotropin-releasing hormone (TRH) | ||||
Synonyms | Prothyroliberin; Pro-thyrotropin-releasing hormone; Pro-TRH | ||||
Target Type | Clinical trial | ||||
Gene Name | TRH | ||||
UniProt ID | TRH_HUMAN | ||||
Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
Disease | Parkinson's disease | ||||
Example drug | KPS-0373 | Phase 3 | [1], [2], [3] | ||
Tissue | Substantia nigra tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.09 Z-score: 0.49 P-value: 2.52E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target's Expression Profile across Various Tissues of Healthy Individual | |||||
References | |||||
REF 1 | ClinicalTrials.gov (NCT01970111) An Extension Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD). U.S. National Institutes of Health. | ||||
REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
REF 3 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. |
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