Target's General Information
Target ID T57011
Target Name ICAM1 messenger RNA (ICAM1 mRNA)
Synonyms Major group rhinovirus receptor (mRNA); Intercellular adhesion molecule 1 (mRNA); ICAM-1 (mRNA); CD54 (mRNA)
Target Type Successful
Gene Name ICAM1
Biochemical Class mRNA target
UniProt ID ICAM1_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Ulcerative colitis
Example drug Alicaforsen Phase 2 [1], [2], [3]
Tissue Colon mucosal tissue
Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section Fold-change: 0.26
Z-score: 0.3
P-value: 1.04E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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