Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T55285 | ||||
| Target Name | Glycine receptor (GlyR) | ||||
| Synonyms | Glycine receptor | ||||
| Target Type | Successful | ||||
| Gene Name | GLRA1; GLRA2; GLRA3; GLRA4; GLRB | ||||
| Biochemical Class | Neurotransmitter receptor | ||||
| UniProt ID | GLRB_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Epilepsy | ||||
| Example drug | MDL-27531 | Phase 1 | [1], [2], [3] | ||
| Tissue | Peritumoral cortex tissue | ||||
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target's Expression Profile across Various Tissues of Healthy Individual | |||||
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| References | |||||
| REF 1 | MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord. Neurosci Lett. 1992 Nov 23;147(1):101-5. | ||||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
| REF 3 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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