Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T49072 | ||||
| Target Name | Urotensin II receptor (UTS2R) | ||||
| Synonyms | Urotensin-II receptor GPR14; UTS2R; UR-II-R; G protein coupled receptor 14 | ||||
| Target Type | Clinical trial | ||||
| Gene Name | UTS2R | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | UR2R_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Asthma | ||||
| Example drug | GlaxoSmithKline | Phase 1 | [1], [2], [3] | ||
| Tissue | Nasal and bronchial airway | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: -0.25 Z-score: -0.57 P-value: 2.85E-02 |
||||
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
|||||
| References | |||||
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2164). | ||||
| REF 2 | ClinicalTrials.gov (NCT01424280) Single Dose Study of GSK1440115 in Patients With Asthma. U.S. National Institutes of Health. | ||||
| REF 3 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.