Target's General Information
Target ID T42928
Target Name Fibroblast growth factor-21 (FGF21)
Synonyms UNQ3115/PRO10196; Fibroblast growth factor 21; FGF-21
Target Type Clinical trial
Gene Name FGF21
Biochemical Class Growth factor
UniProt ID FGF21_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Type 2 diabetes
Example drug PF-05231023 Phase 1 [1], [2], [3]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.05
Z-score: 0.22
P-value: 9.68E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT01923389) Multiple Dose Study Of PF-05231023 In Obese Adult Subjects. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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