Target's General Information
Target ID T35040
Target Name Basigin (BSG)
Synonyms UNQ6505/PRO21383; Tumor cell-derived collagenase stimulatory factor; TCSF; OK blood group antigen; Leukocyte activation antigen M6; Extracellular matrix metalloproteinase inducer; EMMPRIN; 5F7
Target Type Clinical trial
Gene Name BSG
Biochemical Class Basigin protein
UniProt ID BASI_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Liver cancer
Example drug [131I]-Metuximab injection Phase 2 [1], [2], [3]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.88
Z-score: 1.35
P-value: 3.88E-09
Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section Fold-change: 1.31
Z-score: 1.4
P-value: 1.83E-34
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT00819650) A Trial of Licartin for Preventing Tumor Recurrence After Liver Resection. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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