Target's General Information
Target ID T23212
Target Name Monocyte differentiation antigen CD14 (CD14)
Synonyms Myeloid cell-specific leucine-rich glycoprotein
Target Type Clinical trial
Gene Name CD14
UniProt ID CD14_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Sepsis
Example drug IC14 Phase 2 [1], [2], [3]
Tissue Whole blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.61
Z-score: 1.11
P-value: 5.74E-14
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT00233207) IC14 Antibodies to Treat Individuals With Acute Lung Injury. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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