Drug Information
Drug General Information | Top | |||
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Drug ID |
DRA84P
|
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Drug Name |
Tivanisiran
|
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Drug Type |
Small interfering RNA
|
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Indication | Dry eye disease [ICD-11: 9E1Z; ICD-9: 370.33] | Phase 3 | [1] | |
Company |
Sylentis
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | TRPV1 messenger RNA (TRPV1 mRNA) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT04819269) Tivanisiran for Dry Eye in Subjects With Sjogren's Syndrome. U.S. National Institutes of Health. | |||
REF 2 | Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426. |
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