Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
DL97UQ
|
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Drug Name |
A337
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|||
Drug Type |
Bispecific antibody
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|||
Indication | Aggressive cancer [ICD-11: 2A00-2F9Z; ICD-10: R45.6; ICD-9: 140-229] | Phase 1 | [1] | |
Company |
Klus Pharma
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Cytotoxic T-lymphocyte protein 4 (CTLA-4) | Target Info | . | [1] |
Programmed cell death 1 ligand 1 (PD-L1) | Target Info | . | [1] | |
KEGG Pathway | Cell adhesion molecules (CAMs) | |||
T cell receptor signaling pathway | ||||
Autoimmune thyroid disease | ||||
Rheumatoid arthritis | ||||
Pathway Interaction Database | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||
Reactome | CTLA4 inhibitory signaling | |||
PD-1 signaling | ||||
WikiPathways | Vitamin D Receptor Pathway | |||
T-Cell Receptor and Co-stimulatory Signaling | ||||
Allograft Rejection | ||||
Costimulation by the CD28 family |
References | Top | |||
---|---|---|---|---|
REF 1 | Clinical pipeline report, company report or official report of Klus Pharma |
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