Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DL74RO
|
|||
| Drug Name |
Virstatin
|
|||
| Synonyms |
88909-96-0; Isodibut; 4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyric acid; 4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid; 4-NAPHTHALIMIDOBUTYRIC ACID; 4-(N-(1,8-naphthalimide))-n-butyric acid; 4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanoic acid; UNII-24SR2Q1Y6M; 24SR2Q1Y6M; MFCD00181400; 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butanoic acid; 1,3-dioxo-1H-Benz[de]isoquinoline-2(3H)-butanoic acid; 4-{2,4-dioxo-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaen-3-yl}butanoic acid; Izodibut; 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butyric acid; ACMC-209qxu; SpecPlus_000928; Spectrum2_000449; Spectrum3_001240; CBMicro_014897; CBKinase1_000229; CBKinase1_012629; BSPBio_002720; CBDivE_001858; CBDivE_003272; MLS001207259; DivK1c_007024; SPBio_000498; CHEMBL403272; SCHEMBL3134908; SCHEMBL3852274; KBio1_001968; KBio3_002220; 1H-Benz(de)isoquinoline-2(3H)-butanoic acid, 1,3-dioxo-; DTXSID10237406; ZINC3884670; ANW-39184; CCG-39963; KM2782; SBB043186; STK395003; AKOS000114634; DG-0077; MCULE-6695567974; NCGC00178507-01; SMR000504925; FT-0734904; ST50049126; X6840; EN300-00247; AB00053241-05; BRD-K60241851-001-02-8; BRD-K60241851-001-06-9; Z56891243; 1h,3H-benzo(de)isoquinoline-2-butyric acid-1,3-dione; F0303-0081; 4-{2,4-Dioxo-3-azatricyclo[7.3.1.0 {5,13}]trideca- 1(13),5,7,9,11-pentaen-3-yl}butanoic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Acinetobacter baumannii infection [ICD-11: CA40.0Y] | Preclinical | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C16H13NO4
|
|||
| Canonical SMILES |
C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCC(=O)O
|
|||
| InChI |
1S/C16H13NO4/c18-13(19)8-3-9-17-15(20)11-6-1-4-10-5-2-7-12(14(10)11)16(17)21/h1-2,4-7H,3,8-9H2,(H,18,19)
|
|||
| InChIKey |
ZHXRDXTYPCPBTI-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 88909-96-0
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vibrio TCP pilus virulence regulatory protein (Vibrio tcpN) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nat Rev Drug Discov. 2017 Jul;16(7):457-471. | |||
| REF 2 | Virstatin inhibits dimerization of the transcriptional activator ToxT. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2372-7. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.