Drug Information
Drug General Information | Top | |||
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Drug ID |
DJF1S3
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Drug Name |
BI 764524
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Drug Type |
Antibody
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Indication | Diabetic retinopathy [ICD-11: 9B71.0; ICD-10: H36.0] | Phase 2 | [1] | |
Company |
boehringer-ingelheim
|
Target and Pathway | Top | |||
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Target(s) | Semaphorin-3A (SEMA3A) | Target Info | . | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT04424290) A First-in Human Trial to Study Safety and Tolerability of Single Rising Intravitreal dOses (Open Label, Non-randomized, Uncontrolled) and in Addition the Early Biological Response of Multiple intravitReal Dosing (Single-masked, raNdomized, Sham-controlled) of BI 764524 in panretinaL Photocoagulation (PRP) Treated proLiferative Diabetic Retinopathy (PDR) Patients With Diabetic Macular Ischemia (DMI) - the HORNBILL Study. U.S.National Institutes of Health. | |||
REF 2 | HORNBILL: a phase I/IIa trial examining the safety, tolerability and early response of BI 764524 in patients with diabetic retinopathy and diabetic macular ischaemia-rationale, study design and protocol. Trials. 2022 Aug 17;23(1):669. |
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