Drug Information
Drug General Information | Top | |||
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Drug ID |
DAQ31P
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Drug Name |
2-aminophenoxazine-3-one
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Synonyms |
Questiomycin A; 2-Amino-3H-phenoxazin-3-one; 2-Aminophenoxazin-3-one; 1916-59-2; 2-Aminophenoxazon; 2-Aminophenoxazone; 3-Aminophenoxazone; 2-Amino-3-phenoxazone; 3H-Phenoxazin-3-one, 2-amino-; Isophenoxazine; 2-amino-phenoxazin-3-one; NSC 94945; MLS000736964; CHEBI:17293; SMR000528446; BRN 0014215; Questinomycine A; 3H-Phenoxazin-3-one,2-amino-; AV toxin C; 2-Aminophenoxazinone; Phx-3 cpd; Phx-3; 2-amino-3-phenoxazinone; 2-azanylphenoxazin-3-one; Acrospermum viticola toxin C; NCIOpen2_006212; 4-27-00-05519 (Beilstein Handbook Reference); cid_72725; CHEMBL146710; SCHEMBL2609261; BDBM76155; DTXSID60172691; HMS2270F19; NSC94945; ZINC4095812; MFCD00207317; NSC-94945; 2-acetylamino-(3h)-phenoxazin-3-one; AKOS027339724; NCGC00246903-01; AS-47041; C02161; J-012388; BRD-K66640612-001-05-8; Q15424786
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Drug Type |
Small molecular drug
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Indication | T-cell leukaemia [ICD-11: 2A90; ICD-10: C86] | Investigative | [1] | |
Structure |
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Download2D MOL |
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Formula |
C12H8N2O2
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Canonical SMILES |
C1=CC=C2C(=C1)N=C3C=C(C(=O)C=C3O2)N
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InChI |
1S/C12H8N2O2/c13-7-5-9-12(6-10(7)15)16-11-4-2-1-3-8(11)14-9/h1-6H,13H2
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InChIKey |
RDJXPXHQENRCNG-UHFFFAOYSA-N
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CAS Number |
CAS 1916-59-2
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:17293
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References | Top | |||
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REF 1 | Anticancer effects of phenoxazine derivatives revealed by inhibition of cell growth and viability, disregulation of cell cycle, and apoptosis induction in HTLV-1-positive leukemia cells. J Pharmacol Sci. 2009 May;110(1):87-97. | |||
REF 2 | Apoptosis as a mechanism for the treatment of adult T cell leukemia: promising drugs from benchside to bedside. Drug Discov Today. 2020 Jul;25(7):1189-1197. |
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