Drug Information
Drug General Information | Top | |||
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Drug ID |
DA5J0E
|
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Drug Name |
RG6512
|
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Drug Type |
Monoclonal antibody
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Indication | Haemophilia A [ICD-11: 3B10.0; ICD-9: 286] | Phase 1 | [1] | |
Company |
Roche
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Coagulation factor IX (F9) | Target Info | . | [1] |
Coagulation factor Xa (F10) | Target Info | . | [1] | |
KEGG Pathway | Complement and coagulation cascades | |||
Panther Pathway | Blood coagulation | |||
Pathwhiz Pathway | Coagulation | |||
Pathway Interaction Database | Beta2 integrin cell surface interactions | |||
Reactome | Extrinsic Pathway of Fibrin Clot Formation | |||
Intrinsic Pathway of Fibrin Clot Formation | ||||
Gamma-carboxylation of protein precursors | ||||
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | ||||
Removal of aminoterminal propeptides from gamma-carboxylated proteins | ||||
Common Pathway of Fibrin Clot Formation | ||||
WikiPathways | Complement and Coagulation Cascades | |||
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | ||||
Blood Clotting Cascade | ||||
Formation of Fibrin Clot (Clotting Cascade) | ||||
Human Complement System |
References | Top | |||
---|---|---|---|---|
REF 1 | Clinical pipeline report, company report or official report of Roche |
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