Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D9Y2KA
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| Drug Name |
4-(4-fluoropyrazol-1-yl)-1,2-oxazol-5-amine
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| Synonyms |
CHEMBL4166624; BDBM50321330
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199] | Preclinical | [1] | |
| Company |
Genentech
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| Structure |
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Download2D MOL |
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| Formula |
C6H5FN4O
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| Canonical SMILES |
C1=C(C=NN1C2=C(ON=C2)N)F
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| InChI |
1S/C6H5FN4O/c7-4-1-9-11(3-4)5-2-10-12-6(5)8/h1-3H,8H2
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| InChIKey |
YCBKZPFCIBXKIG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tryptophan 2,3-dioxygenase (TDO) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Tryptophan metabolism | |||
| Metabolic pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond. Nat Rev Drug Discov. 2019 May;18(5):379-401. | |||
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