Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D9EC0G
|
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| Drug Name |
Zemaira
|
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| Synonyms |
Alpha-1-antitrypsin
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|
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| Drug Type |
Recombinant protein
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| Indication | Emphysema [ICD-11: CA21; ICD-9: 492] | Approved | [1] | |
| Company |
CSL Behring
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| ADReCS Drug ID | BADD_D00084 | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Alpha-1-antitrypsin (SERPINA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Complement and coagulation cascades | |||
| NetPath Pathway | IL6 Signaling Pathway | |||
| Panther Pathway | Blood coagulation | |||
| Pathway Interaction Database | p73 transcription factor network | |||
| FOXA1 transcription factor network | ||||
| Reactome | Platelet degranulation | |||
| COPII (Coat Protein 2) Mediated Vesicle Transport | ||||
| Cargo concentration in the ER | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. | |||
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