Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D6VLX2
|
|||
| Drug Name |
JNJ-42905343
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Anaemia [ICD-11: 3A90; ICD-10: D64.8] | Preclinical | [1] | |
| Iron deficiency [ICD-11: 5B5K.0; ICD-10: E61.1; ICD-9: 280.9] | Preclinical | [1] | ||
| Company |
Janssen
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HIF-prolyl hydroxylase (HPH) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Targeting iron metabolism in drug discovery and delivery. Nat Rev Drug Discov. 2017 Jun;16(6):400-423. | |||
| REF 2 | Prolyl hydroxylase inhibition corrects functional iron deficiency and inflammation-induced anaemia in rats. Br J Pharmacol. 2015 Aug;172(16):4078-88. | |||
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