Drug Information
Drug General Information | Top | |||
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Drug ID |
D6KEW7
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Drug Name |
YG1699
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Drug Type |
Small molecule
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Indication | Type-1 diabetes [ICD-11: 5A10] | Phase 2 | [1] | |
Company |
Youngene Therapeutics Shanghai, China
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Sodium/glucose cotransporter 1 (SGLT1) | Target Info | Inhibitor | [1] |
Sodium/glucose cotransporter 2 (SGLT2) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Carbohydrate digestion and absorption | |||
Bile secretion | ||||
Mineral absorption | ||||
Pathwhiz Pathway | Lactose Degradation | |||
Trehalose Degradation | ||||
Reactome | Hexose transport | |||
Na+-dependent glucose transporters | ||||
Inositol transporters | ||||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
Metabolism of carbohydrates |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT04956263) A Comparison of Postprandial Glucose After a Mixed Meal Tolerance Test, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study of the Dual Systemic SGLT1 and SGLT2 Inhibitor YG1699, and the Selective SGLT2 Inhibitor Dapagliflozin in Subjects With Type 1 Diabetes. U.S.National Institutes of Health. |
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