Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D2ZI3H
|
|||
| Drug Name |
BNC-102
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199] | Preclinical | [1] | |
| Company |
Bionomics
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | G-protein coupled receptor 48 (LGR4) | Target Info | Inhibitor | [2] |
| Leucine-rich repeat-containing GPCR 5 (LGR5) | Target Info | Inhibitor | [2] | |
| Reactome | Regulation of FZD by ubiquitination | |||
| WikiPathways | Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Opportunities for therapeutic antibodies directed at G-protein-coupled receptors. Nat Rev Drug Discov. 2017 Sep;16(9):787-810. | |||
| REF 2 | Opportunities for therapeutic antibodies directed at G-protein-coupled receptors. Nat Rev Drug Discov. 2017 Sep 1;16(9):661. | |||
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