Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0ZU3S
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| Former ID |
DNC003761
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| Drug Name |
PS-777621
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| Synonyms |
PS-777621; CHEMBL318055; BDBM50146527; (S)-3-(S)-Hydroxy-6-methyl-4-{(S)-3-methyl-2-[2-(naphthalen-2-yloxy)-acetylamino]-pentanoylamino}-heptanoic acid butylamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C30H45N3O5
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| Canonical SMILES |
CCCCNC(=O)CC(C(CC(C)C)NC(=O)C(C(C)CC)NC(=O)COC1=CC2=CC=CC=C2C=C1)O
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| InChI |
1S/C30H45N3O5/c1-6-8-15-31-27(35)18-26(34)25(16-20(3)4)32-30(37)29(21(5)7-2)33-28(36)19-38-24-14-13-22-11-9-10-12-23(22)17-24/h9-14,17,20-21,25-26,29,34H,6-8,15-16,18-19H2,1-5H3,(H,31,35)(H,32,37)(H,33,36)/t21?,25-,26-,29-/m0/s1
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| InChIKey |
ZOZZWZVOMAKBJD-BGRUSPQTSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Plasmepsin 1 (Malaria PLA1) | Target Info | Inhibitor | [1] |
| Plasmodium Plasmepsin 2 (Malaria PLA2) | Target Info | Inhibitor | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | High antiplasmodial activity of novel plasmepsins I and II inhibitors. J Med Chem. 2006 Dec 14;49(25):7440-9. | |||
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