Drug Information
Drug General Information | Top | |||
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Drug ID |
D0ZO8Z
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Former ID |
DNC006684
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Drug Name |
2-(3,4-dimethoxybenzamido)thiophene-3-carboxamide
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Synonyms |
2-(3,4-dimethoxybenzamido)thiophene-3-carboxamide; CHEMBL210622; MolPort-003-062-950; ZINC4275736; AC1N3474; BDBM50185082; AKOS024605336; MCULE-1480938066; SR-01000011723; SR-01000011723-1; F1358-0295; 2-[(3,4-dimethoxybenzoyl)amino]thiophene-3-carboxamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H14N2O4S
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Canonical SMILES |
COC1=C(C=C(C=C1)C(=O)NC2=C(C=CS2)C(=O)N)OC
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InChI |
1S/C14H14N2O4S/c1-19-10-4-3-8(7-11(10)20-2)13(18)16-14-9(12(15)17)5-6-21-14/h3-7H,1-2H3,(H2,15,17)(H,16,18)
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InChIKey |
LORRZRFBMUDPOE-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Fms-like tyrosine kinase 3 (FLT-3) | Target Info | Inhibitor | [1] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
Hematopoietic cell lineage | ||||
Pathways in cancer | ||||
Transcriptional misregulation in cancer | ||||
Acute myeloid leukemia | ||||
Central carbon metabolism in cancer |
References | Top | |||
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REF 1 | Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. |
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