Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0ZG4G
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| Former ID |
DNC006005
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| Drug Name |
FR-180204
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| Synonyms |
865362-74-9; FR 180204; FR180204; FR-180204; ERK Inhibitor II, FR180204; 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine; CHEMBL259551; 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE; C18H13N7; 5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-1H-pyrazolo[3,4-c]pyridazin-3-amine; 5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-2H-pyrazolo[3,4-c]pyridazin-3-amine; 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine; ERK inhibitor II; MLS002607685
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H13N7
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| Canonical SMILES |
C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=CC5=C(NN=C5N=N4)N
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| InChI |
1S/C18H13N7/c19-17-12-10-13(20-22-18(12)23-21-17)15-14-8-4-5-9-25(14)24-16(15)11-6-2-1-3-7-11/h1-10H,(H3,19,21,22,23)
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| InChIKey |
XVECMUKVOMUNLE-UHFFFAOYSA-N
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| CAS Number |
CAS 865362-74-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
16595520, 26758672, 42572462, 78319999, 99302705, 99444265, 103567636, 104098227, 118855303, 123389850, 125001301, 125434282, 134343210, 137184700, 152133961, 160968857, 163124396, 163688169, 172131330, 174006438, 174811337, 175607474, 178102589, 180371711, 180387045, 187071940, 198043968, 210274775, 210280408, 223704845, 227977648, 239980481, 251910756, 252157471, 252160370, 252554246
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| ChEBI ID |
CHEBI:91383
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5966). | |||
| REF 2 | Crystal structure of human ERK2 complexed with a pyrazolo[3,4-c]pyridazine derivative. Bioorg Med Chem Lett. 2006 Jan 1;16(1):55-8. | |||
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