Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z8LA
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| Former ID |
DIB001454
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| Drug Name |
Cyclocreatine
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| Synonyms |
Cyclocreatinine; AM-285
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| Drug Type |
Small molecular drug
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| Indication | Virus infection [ICD-11: 1A24-1D9Z] | Discontinued in Phase 1 | [1], [2] | |
| Company |
Repligen Corp
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| Structure |
 |
Download2D MOL |
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| Formula |
C5H9N3O2
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| Canonical SMILES |
C1CN(C(=N1)N)CC(=O)O
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| InChI |
1S/C5H9N3O2/c6-5-7-1-2-8(5)3-4(9)10/h1-3H2,(H2,6,7)(H,9,10)
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| InChIKey |
AMHZIUVRYRVYBA-UHFFFAOYSA-N
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| CAS Number |
CAS 35404-50-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
529572, 3158677, 3723557, 6061236, 7407343, 7980747, 8149819, 11335658, 11360897, 11364383, 11366945, 11369507, 11372750, 11373816, 11377669, 11442635, 11461869, 11484566, 11488741, 11491321, 11492144, 11495303, 14747788, 15146741, 24863514, 26612294, 26679264, 26748607, 26748608, 29222049, 46386859, 47365137, 47662232, 48334442, 50070276, 50070944, 50107434, 51834597, 57321503, 88813858, 92124430, 99301571, 103100948, 103444751, 104301934, 117549196, 117611160, 117673335, 118802878, 124637504
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Protein kinase (PK) | Target Info | Inhibitor | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5491). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002859) | |||
| REF 3 | Direct determination of creatine kinase equilibrium constants with creatine or cyclocreatine substrate. Biochim Biophys Acta. 1989 Oct 19;998(3):317-20. | |||
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