Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z7YI
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| Former ID |
DNC014609
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| Drug Name |
2-Propionyl-1H-indole-6-carboxamidine
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| Synonyms |
CHEMBL321960; 2-Propionyl-1H-indole-6-carboxamidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H13N3O
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| Canonical SMILES |
CCC(=O)C1=CC2=C(N1)C=C(C=C2)C(=N)N
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| InChI |
1S/C12H13N3O/c1-2-11(16)10-5-7-3-4-8(12(13)14)6-9(7)15-10/h3-6,15H,2H2,1H3,(H3,13,14)
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| InChIKey |
MUIPXQPVWYRDNF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cationic trypsinogen (PRSS1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Influenza A | ||||
| Reactome | Activation of Matrix Metalloproteinases | |||
| Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
| WikiPathways | Activation of Matrix Metalloproteinases | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin... J Med Chem. 1983 Feb;26(2):294-8. | |||
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