Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z1RV
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| Former ID |
DAP000029
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| Drug Name |
Clozapine
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| Synonyms |
Asaleptin; CLOZARIL; Clorazil; Clozapin; Clozapina; Clozapinum; Fazaclo; Iprox; Leponex; Lepotex; Fazaclo ODT; C 6305; HF1854; Clopine (TN); Clozapina [INN-Spanish]; Clozapine(tautomer); Clozapinum [INN-Latin]; Clozaril (TN); Denzapine (TN); Fazaclo (TN); Froidir (TN); HF-1854; KS-1166; Klozapol (TN); LEX-123; LX 100-129; Leponex (TN); W-801; Zaponex (TN); Clozapine [USAN:INN:BAN]; Clozapine (JAN/USP/INN); 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine; 8-Chloro-11-(4-methyl)-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b,e)(1,4)diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine; 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine; 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
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| Drug Type |
Small molecular drug
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| Indication | Schizophrenia [ICD-11: 6A20] | Approved | [1], [2] | |
| Therapeutic Class |
Antipsychotic Agents
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| Company |
Sandoz
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| Structure |
 |
Download2D MOL |
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| Formula |
C18H19ClN4
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| Canonical SMILES |
CN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42
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| InChI |
1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
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| InChIKey |
QZUDBNBUXVUHMW-UHFFFAOYSA-N
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| CAS Number |
CAS 5786-21-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9141, 631806, 855811, 4821023, 7847349, 7978980, 8004367, 8149634, 10321650, 10528074, 11110967, 11110968, 11113341, 11120316, 11120804, 11121292, 11121655, 11122135, 11335518, 11360757, 11362724, 11363013, 11365286, 11365575, 11367848, 11368137, 11370719, 11370720, 11373074, 11373449, 11374475, 11376010, 11376299, 11461729, 11466378, 11467498, 11484534, 11486076, 11488735, 11491643, 11492713, 11493953, 12013419, 14826474, 17404839, 24277892, 26612026, 26680236, 26747001, 26747002
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| ChEBI ID |
CHEBI:3766
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| ADReCS Drug ID | BADD_D00511 | |||
| SuperDrug ATC ID |
N05AH02
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| SuperDrug CAS ID |
cas=005786210
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 38). | |||
| REF 2 | The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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