Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Z0ZM
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Drug Name |
SB-202235
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Synonyms |
139149-55-6; SB-202236
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
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Download2D MOL |
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Formula |
C10H12N2O4
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Canonical SMILES |
COC1=CC2=C(C=C1)C(CO2)N(C(=O)N)O
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InChI |
1S/C10H12N2O4/c1-15-6-2-3-7-8(12(14)10(11)13)5-16-9(7)4-6/h2-4,8,14H,5H2,1H3,(H2,11,13)/t8-/m1/s1
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InChIKey |
KQTIJEDPTHQHRM-MRVPVSSYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Modulator | [1] |
BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
Resolvin D biosynthesis | ||||
Leukotriene biosynthesis | ||||
Lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | ||||
Aspirin triggered resolvin E biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Ovarian steroidogenesis | ||||
Toxoplasmosis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Vitamin D Receptor Pathway | |||
Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Pharmacological characterization of SB 202235, a potent and selective 5-lipoxygenase inhibitor: effects in models of allergic asthma. J Pharmacol Exp Ther. 1995 Jun;273(3):1147-55. |
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