Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YW6P
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| Former ID |
DIB014762
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| Drug Name |
RU-101
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| Synonyms |
RU-10; Recombinant human serum albumin (ocular, dry eye), R-Tech Ueno
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| Indication | Xerophthalmia [ICD-11: 5B55.Y] | Phase 1/2 | [1] | |
| Company |
R-tech ueno
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serum albumin (ALB) | Target Info | Modulator | [2] |
| Pathway Interaction Database | FOXA2 and FOXA3 transcription factor networks | |||
| Reactome | Platelet degranulation | |||
| Recycling of bile acids and salts | ||||
| HDL-mediated lipid transport | ||||
| Scavenging of heme from plasma | ||||
| WikiPathways | Human Complement System | |||
| Binding and Uptake of Ligands by Scavenger Receptors | ||||
| Lipid digestion, mobilization, and transport | ||||
| Transport of vitamins, nucleosides, and related molecules | ||||
| Bile acid and bile salt metabolism | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01843894) A Phase 1/2, RU-101 Ophthalmic Solution in Patients With Severe Dry Eye. U.S. National Institutes of Health. | |||
| REF 2 | Albumin as a tear supplement in the treatment of severe dry eye. Br J Ophthalmol. 2003 October; 87(10): 1279-1283. | |||
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