Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YS7D
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| Former ID |
DAP001058
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| Drug Name |
Isosorbide Mononitrate
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| Synonyms |
Conpin; Corangin; Duride; Edistol; Elantan; Epicordin; Etimonis; IHD; ISMN; ISMO; Imazin; Imdur; Imodur; Imtrate; Ismexin; Ismox; Isomon; Isomonat; Isomonit; Iturol; Medocor; Monicor; Monis; Monisid; Monit; Monizid; MonoSigma; Monocedocard; Monocinque; Monoclair; Monocord; Monoket; Monolong; Monomax; Mononit; Monopront; Monosorb; Monosorbitrate; Monosordil; Monotrate; Multitab; Nitex; Nitramin; Olicard; Olicardin; Orasorbil; Percorina; Pertil; Plodin; Promocard; Sigacora; Sorbimon; Titarane; Turimonit; Uniket; Vasdilat; Vasotrate; Conpin Retardkaps; Corangin SR; Elantan Long; Elantan Retard; ISMN AL; ISMN AbZ; ISMN Apogepha; ISMN Atid; ISMN Basics; ISMN Heumann; ISMN Hexal; ISMN Lannacher; ISMN Stada; Imdur Durules; Isosorbidi mononitras; Isosorbidi mononitras [Latin]; Mono Corax; Mono Corax Retard; Mono Mack; Monodur Durules; Monoket OD; Monoket Retard; Mononitrato de isosorbida; Mononitrato de isosorbida [Spanish]; AHR 4698; IS 5MN; Imdur 60; Monit 20; Mono Mac 50D; Monocord 20; Monocord 40; Monocord 50 SR; Monolong 40; Monolong 60; Mononit 20; Mononit 40; Mononit Retard 50; Monosorb XL 60;Olicard 40; Pentacard 20; AHR-4698; BM 22-145; BM 22.145; Chemydur (TN); Fem-Mono; IS 5-MN; Imdur (TN); Ismo (TN); Ismo-20; Isopen-20; Isosorbide 5-mononitrate; Isosorbide 5-nitrate; Mono-Mack; Mono-Sanorania; Mononitrate d'isosorbide; Mononitrate d'isosorbide [French]; Olicard-retard; BM-22-145; Isosobide-5-mononitrate [UN3251] [Flammable solid]; Isosorbide-5-mononitrate; Isosorbide-5-nitrate; Isosorbide mononitrate (JAN/USP/INN); Isosorbide mononitrate [USAN:BAN:INN:JAN]; Isosorbide mononitrate [USAN:INN:BAN:JAN]; D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate; [(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate; 1,4:3,6-Dianhydro-D-glucitol 5-nitrate; 1,4:3,6-dianhydro-5-O-nitro-D-glucitol; 5-ISMN Durules; 5-Ismn
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| Drug Type |
Small molecular drug
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| Indication | Hydrocephalus [ICD-11: 8D64] | Approved | [1] | |
| Therapeutic Class |
Vasodilator Agents
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| Company |
AstraZeneca
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| Structure |
 |
Download2D MOL |
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| Formula |
C6H9NO6
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| Canonical SMILES |
C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O
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| InChI |
1S/C6H9NO6/c8-3-1-11-6-4(13-7(9)10)2-12-5(3)6/h3-6,8H,1-2H2/t3-,4+,5+,6+/m0/s1
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| InChIKey |
YWXYYJSYQOXTPL-SLPGGIOYSA-N
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| CAS Number |
CAS 16051-77-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9916, 1996243, 3140015, 7847696, 7979662, 8169915, 14748507, 15171521, 34670166, 46506594, 48416135, 49972423, 50113025, 53801154, 57310486, 78898435, 87325445, 87571756, 92308037, 103408641, 104231660, 104300601, 109658188, 115354129, 117383795, 125311718, 126603354, 126608841, 126616754, 126665019, 129859949, 134338317, 134992567, 136903837, 137003475, 142599818, 143449442, 144075642, 144205134, 152165118, 152250184, 160808664, 160964356, 163087759, 163589576, 164811402, 175266479, 175610990, 176266501, 177748777
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| ChEBI ID |
CHEBI:6062
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| ADReCS Drug ID | BADD_D01211 | |||
| SuperDrug ATC ID |
C01DA14
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| SuperDrug CAS ID |
cas=016051777
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Guanylate cyclase (GC) | Target Info | Stimulator | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart. Mol Cell Biochem. 2010 Jan;333(1-2):191-201. | |||
| REF 3 | Cervical priming in the first trimester: morphological and biochemical effects of misoprostol and isosorbide mononitrate. Acta Obstet Gynecol Scand. 2009;88(1):43-51. | |||
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