Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0YN1A
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| Former ID |
DIB019183
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| Drug Name |
PMID24900526C1
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| Synonyms |
107491-28-1; AC1LHVED; BAS 06984707; CBKinase1_016190; CBKinase1_003790; MLS000124060; GTPL7870; CTK7J5343; MolPort-002-007-625; ZINC470145; MFCD03876460; BDBM50400562; AKOS000302705; MCULE-5295604199; SMR000124614; DB-016663; TR-042640; ST50281836
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C14H13NO4S
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)NCC(=O)O
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| InChI |
1S/C14H13NO4S/c16-14(17)10-15-20(18,19)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,15H,10H2,(H,16,17)
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| InChIKey |
ZIAFXLGSGMQYPL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3591766, 4099285, 4806661, 9188561, 16952388, 44496212, 47587372, 47809222, 49800299, 53451733, 85840632, 89050593, 94103255, 104849914, 110043808, 117658981, 125423449, 129905619, 135562846, 143694509, 160978063, 163070257, 163336469, 163349586, 168525128, 179248669, 203089496, 224877117, 236133109, 249565575
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Matrix metalloproteinase-12 (MMP-12) | Target Info | Inhibitor | [1] |
| NetPath Pathway | IL1 Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
| Reactome | Collagen degradation | |||
| Degradation of the extracellular matrix | ||||
| WikiPathways | TGF beta Signaling Pathway | |||
| Degradation of collagen | ||||
| Matrix Metalloproteinases | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Target-Activated Prodrugs (TAPs) for the Autoregulated Inhibition of MMP12. ACS Med Chem Lett. 2012 Jul 14;3(8):653-7. | |||
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