Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YM3G
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| Drug Name |
Pyrrolo-pyrrolone derivative 1
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| Synonyms |
PMID26924192-Compound-34
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| Drug Type |
Small molecular drug
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| Company |
NOVARTIS AG [CHBLANK JUTTA [CHBOLD GUIDO [CHBORDAS VINCENT [CHCOTESTA SIMONA [CHGUAGNANO VITO [CHR EGER HEINRICH [CHVAUPEL ANDREA [CH]
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| Structure |
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Download2D MOL |
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| Formula |
C28H27ClN6O2
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| Canonical SMILES |
CC1=CC(=CN2C1=NN=C2C)N3C(C4=C(C3=O)C(=CN4C5CN(C5)C(=O)C)C6CC6)C7=CC=C(C=C7)Cl
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| InChI |
1S/C28H27ClN6O2/c1-15-10-21(13-33-16(2)30-31-27(15)33)35-25(19-6-8-20(29)9-7-19)26-24(28(35)37)23(18-4-5-18)14-34(26)22-11-32(12-22)17(3)36/h6-10,13-14,18,22,25H,4-5,11-12H2,1-3H3
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| InChIKey |
CASINEGODQBEAL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bromodomain-containing protein 2 (BRD2) | Target Info | Inhibitor | [1] |
| Bromodomain-containing protein 3 (BRD3) | Target Info | Inhibitor | [1] | |
| Bromodomain-containing protein 4 (BRD4) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Bromodomain-containing protein 2 (BRD2) | Target's Patent Info | [1] | |
| Bromodomain-containing protein 3 (BRD3) | Target's Patent Info | [1] | ||
| Bromodomain-containing protein 4 (BRD4) | Target's Patent Info | [1] | ||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Regulation of retinoblastoma protein | |||
| WikiPathways | Chemical Compounds to monitor Proteins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | BET inhibitors in cancer therapeutics: a patent review.Expert Opin Ther Pat. 2016;26(4):505-22. | |||
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