Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YE2N
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| Former ID |
DIB011301
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| Drug Name |
Eperezolid
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| Synonyms |
PNU-100592; U-100592
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Discontinued in Phase 3 | [1] | |
| Company |
Pharmacia & Upjohn Co
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| Structure |
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Download2D MOL |
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| Formula |
C18H23FN4O5
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| Canonical SMILES |
CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)CO)F
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| InChI |
1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1
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| InChIKey |
SIMWTRCFFSTNMG-AWEZNQCLSA-N
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| CAS Number |
CAS 165800-04-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial 50S ribosomal RNA (Bact 50S rRNA) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005626) | |||
| REF 2 | The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. | |||
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