Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Y9ZE
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Former ID |
DAP000150
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Drug Name |
Milrinone
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Synonyms |
Corotrop; Corotrope; Milrila; Milrinona; Milrinonum; Primacor; Milrinona [Spanish]; Milrinonum [Latin]; M 4659; M1663; YM 018; MILRINONE LACTATE IN DEXTROSE 5% IN PLASTIC CONTAINER; Milrila (TN); PRIMACOR IN DEXTROSE 5% IN PLASTIC CONTAINER; Primacor (TN); WIN 47203-2; Win-47203; Milrinone [USAN:BAN:INN]; Win-47203-2; Milrinone (JAN/USAN/INN); 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile; 1,6-Dihydro-2-methyl-6-oxo-(3,4′-bipyridine)-5-carbonitrile; 1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile; 1,6-Dihydro-2-methyl-6-oxo-3,4-bipyridine-5-carbonitrile; 1,6-Dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile; 111GE027; 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile; 3-Cyano-6-methyl-5-(4-pyridyl)-2-pyridone; 6-Methyl-5-(4-pyridyl)-2-pyridone-3-carbonitrile; 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
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Drug Type |
Small molecular drug
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Indication | Congestive heart failure [ICD-11: BD10; ICD-10: I50.0; ICD-9: 428] | Approved | [1], [2] | |
Therapeutic Class |
Cardiotonic Agents
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Company |
Sanofi-Synthelabo Inc
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Structure |
Download2D MOL |
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Formula |
C12H9N3O
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Canonical SMILES |
CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2
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InChI |
1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
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InChIKey |
PZRHRDRVRGEVNW-UHFFFAOYSA-N
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CAS Number |
CAS 78415-72-2
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PubChem Compound ID | ||||
PubChem Substance ID |
9433, 7433693, 7847483, 7979998, 8152624, 11111460, 11111461, 11114110, 11467093, 11468213, 11486701, 11532967, 12013065, 14773322, 14797712, 17405298, 24278060, 26757809, 26759173, 29223302, 46386629, 46507838, 46509455, 47291218, 47589081, 47736585, 48035233, 48185083, 48416283, 49681694, 49699274, 49894545, 50104873, 50104874, 50492767, 53777843, 53787311, 56352862, 57322187, 72604407, 81041060, 81061337, 85087897, 85231135, 87577949, 90341667, 92125976, 92304231, 92308460, 92309190
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ChEBI ID |
CHEBI:50693
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ADReCS Drug ID | BADD_D01467 ; BADD_D01468 | |||
SuperDrug ATC ID |
C01CE02
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SuperDrug CAS ID |
cas=078415722
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Target and Pathway | Top | |||
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Target(s) | Phosphodiesterase 3 (PDE3) | Target Info | Modulator | [3] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5225). | |||
REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. |
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