Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Y8YN
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| Former ID |
DNC014592
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| Drug Name |
(3-Amino-propyl)-hexyl-phosphinic acid
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| Synonyms |
3-Aminopropyl(hexyl)phosphinic acid; 3-Aphpa; 123691-31-6; 3-Aminopropyl(n-hexyl)phosphinic acid; CHEMBL113571; Phosphinic acid,(3-aminopropyl)hexyl- (9CI); ACMC-20mqpl; (3-Amino-propyl)-hexyl-phosphinic acid; AC1L2WN2; SCHEMBL6354602; CTK4B3595; DTXSID90154066
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H22NO2P
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| Canonical SMILES |
CCCCCCP(=O)(CCCN)O
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| InChI |
1S/C9H22NO2P/c1-2-3-4-5-8-13(11,12)9-6-7-10/h2-10H2,1H3,(H,11,12)
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| InChIKey |
QVUUPQCCYOPHFY-UHFFFAOYSA-N
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| CAS Number |
CAS 123691-31-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| GABAergic synapse | ||||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | Activation of G protein gated Potassium channels | |||
| G alpha (i) signalling events | ||||
| Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
| WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Potassium Channels | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity, Bioorg. Med. Chem. Lett. 3(4):515-518 (1993). | |||
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