Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Y4OI
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Former ID |
DIB000582
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Drug Name |
SKF-105809
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Synonyms |
SKF-105561
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Drug Type |
Small molecular drug
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Indication | Pain [ICD-11: MG30-MG3Z] | Phase 1 | [1] | |
Company |
SmithKline Beecham plc
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Structure |
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Download2D MOL |
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Formula |
C18H17N3OS
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Canonical SMILES |
CS(=O)C1=CC=C(C=C1)C2=C(N3CCCC3=N2)C4=CC=NC=C4
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InChI |
1S/C18H17N3OS/c1-23(22)15-6-4-13(5-7-15)17-18(14-8-10-19-11-9-14)21-12-2-3-16(21)20-17/h4-11H,2-3,12H2,1H3
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InChIKey |
KSEJZTWORQXILM-UHFFFAOYSA-N
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CAS Number |
CAS 122454-69-7
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
Prostaglandin G/H synthase (COX) | Target Info | Modulator | [1] | |
BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
Resolvin D biosynthesis | ||||
Leukotriene biosynthesis | ||||
Lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | ||||
Aspirin triggered resolvin E biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Ovarian steroidogenesis | ||||
Toxoplasmosis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Vitamin D Receptor Pathway | |||
Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Analgetic activity of SK&F 105809, a dual inhibitor of arachidonic acid metabolism. Agents Actions Suppl. 1991;32:113-7. |
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