Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Y4AZ
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Former ID |
DIB011637
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Drug Name |
Galocitabine
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Synonyms |
Galocitabine; Ro-09-1390; N-[1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydro-4-pyrimidinyl]-3,4,5-trimethoxybenzamide; 5'-Deoxy-5-fluoro-N4-(3,4,5-trimethoxybenzoyl)cytidine
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Drug Type |
Small molecular drug
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Discontinued in Phase 3 | [1] | |
Structure |
Download2D MOL |
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Formula |
C19H22FN3O8
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Canonical SMILES |
CC1C(C(C(O1)N2C=C(C(=NC2=O)NC(=O)C3=CC(=C(C(=C3)OC)OC)OC)F)O)O
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InChI |
1S/C19H22FN3O8/c1-8-13(24)14(25)18(31-8)23-7-10(20)16(22-19(23)27)21-17(26)9-5-11(28-2)15(30-4)12(6-9)29-3/h5-8,13-14,18,24-25H,1-4H3,(H,21,22,26,27)/t8-,13-,14-,18-/m1/s1
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InChIKey |
TVYPSLDUBVTDIS-FUOMVGGVSA-N
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CAS Number |
CAS 124012-42-6
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PubChem Compound ID |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002535) | |||
REF 2 | The role of thymidylate synthase in cellular regulation. Adv Enzyme Regul. 1996;36:143-63. |
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