Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y2HA
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| Former ID |
DIB000669
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| Drug Name |
Pramiconazole
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| Synonyms |
Azoline; Antifungals, Janssen Research Foundation; R-126638
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| Drug Type |
Small molecular drug
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| Indication | Dermatological disease [ICD-11: DA24.Y] | Phase 2 | [1] | |
| Company |
Barrier Therapeutics
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| Structure |
 |
Download2D MOL |
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| Formula |
C35H39F2N7O4
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| Canonical SMILES |
CC(C)N1CCN(C1=O)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5OCC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F
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| InChI |
1S/C35H39F2N7O4/c1-25(2)43-17-18-44(34(43)45)29-6-4-27(5-7-29)40-13-15-41(16-14-40)28-8-10-30(11-9-28)46-20-33-47-22-35(48-33,21-42-24-38-23-39-42)31-12-3-26(36)19-32(31)37/h3-12,19,23-25,33H,13-18,20-22H2,1-2H3/t33-,35+/m0/s1
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| InChIKey |
AEKNYBWUEYNWMJ-QWOOXDRHSA-N
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| CAS Number |
CAS 219923-85-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Candida Cytochrome P450 51 (Candi ERG11) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The efficacy of oral treatment with pramiconazole in pityriasis versicolor: a phase II a trial. Br J Dermatol. 2007 Jun;156(6):1385-8. | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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