Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y1TA
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| Former ID |
DNC009855
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| Drug Name |
2,4'-Diacetoxy-5,3'-di-(2-propenyl)-biphenyl
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| Synonyms |
CHEMBL570311; Diacetylhonokiol; SCHEMBL18313888; BDBM50295922
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H22O4
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| Canonical SMILES |
CC(=O)OC1=C(C=C(C=C1)C2=C(C=CC(=C2)CC=C)OC(=O)C)CC=C
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| InChI |
1S/C22H22O4/c1-5-7-17-9-11-22(26-16(4)24)20(13-17)18-10-12-21(25-15(3)23)19(14-18)8-6-2/h5-6,9-14H,1-2,7-8H2,3-4H3
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| InChIKey |
XNFZWGDLKCJOLJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | LOX-5 messenger RNA (ALOX5 mRNA) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxyge... Bioorg Med Chem. 2009 Jul 1;17(13):4459-65. | |||
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