Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Y0BK
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| Former ID |
DNC014891
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| Drug Name |
Dorsomorphin
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| Synonyms |
dorsomorphin; 866405-64-3; 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine; BML-275; Compound C; AMPK Inhibitor, Compound C; 6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine; CHEMBL478629; CHEBI:78510; 4-(6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}pyrazolo[1,5-a]pyrimidin-3-yl)pyridine; 6-[4-(2-Piperidin-1-yl-ethoxy)-phenyl)]-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine; AMPK Inhibitor
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C24H25N5O
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| Canonical SMILES |
C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3
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| InChI |
1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
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| InChIKey |
XHBVYDAKJHETMP-UHFFFAOYSA-N
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| CAS Number |
CAS 866405-64-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
16626128, 23651006, 24898658, 26740883, 26758223, 26758224, 29217627, 53786887, 53800969, 53800970, 75175553, 85788231, 98570042, 99302626, 99431644, 99445068, 103623641, 104111291, 104548349, 119524662, 121279095, 124893194, 125503629, 126661319, 131328479, 131538258, 134352096, 135282172, 135711804, 136899197, 137864951, 160835058, 160969630, 163230883, 163400671, 163688604, 163688605, 164041743, 166200007, 172821450, 174006502, 175607457, 178101606, 179694515, 204384696, 208265176, 210274852, 210280484, 223443838, 223573618
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| ChEBI ID |
CHEBI:78510
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4907). | |||
| REF 2 | The rational design of a novel potent analogue of the 5'-AMP-activated protein kinase inhibitor compound C with improved selectivity and cellular a... Bioorg Med Chem Lett. 2010 Nov 15;20(22):6394-9. | |||
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