Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0XX9G
|
|||
| Former ID |
DNC014559
|
|||
| Drug Name |
(3-Amino-propyl)-hydroxymethyl-phosphinic acid
|
|||
| Synonyms |
AC1MTETN; SCHEMBL341290; MolPort-002-514-611; STL513587; ZINC20112625; AKOS030493595; MCULE-2944312169; 3-aminopropyl(hydroxymethyl)phosphinic acid; (Hydroxymethyl)(3-aminopropyl)phosphinic acid; (3-aminopropyl)(hydroxymethyl)phosphinic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C4H11NO3P+
|
|||
| Canonical SMILES |
C(CN)C[P+](C=O)(O)O
|
|||
| InChI |
1S/C4H11NO3P/c5-2-1-3-9(7,8)4-6/h4,7-8H,1-3,5H2/q+1
|
|||
| InChIKey |
WKJVZSFFUHQPOM-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| GABAergic synapse | ||||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | Activation of G protein gated Potassium channels | |||
| G alpha (i) signalling events | ||||
| Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
| WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Potassium Channels | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists. J Med Chem. 1995 Aug 18;38(17):3297-312. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.