Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0XQ8A
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| Former ID |
DIB001132
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| Drug Name |
TPN-729
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| Synonyms |
TPN-729B; PDE5 inhibitors (erectile dysfunction/pulmonary arterial hypertension), Shanghai Institute of Materia Medica/Topharman Shanghai
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| Indication | Erectile dysfunction [ICD-11: HA01.1; ICD-10: N48.4; ICD-9: 302.72, 607.84] | Investigative | [1] | |
| Company |
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 5A (PDE5A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Reactome | cGMP effects | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1304). | |||
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