Drug Information
Drug General Information | Top | |||
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Drug ID |
D0XN5L
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Former ID |
DIB003146
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Drug Name |
Albutropin
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Synonyms |
Albumin-based fusion protein (growth deficiency), Teva Pharmaceutical; Recombinant human growth hormone (HGH, long acting),Human Genome Sciences; Albumin-based fusion protein (growth deficiency), Principia (HGS); Recombinant human growth hormone (HGH, long-acting), Teva Pharmaceutical
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Indication | Growth failure [ICD-11: LD2F.1Y] | Phase 3 | [1] | |
Company |
Aventis Behring LLC
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Target and Pathway | Top | |||
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Target(s) | Somatotropin (GH1) | Target Info | Modulator | [2] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
Neuroactive ligand-receptor interaction | ||||
PI3K-Akt signaling pathway | ||||
Jak-STAT signaling pathway | ||||
Reactome | Prolactin receptor signaling | |||
Growth hormone receptor signaling | ||||
WikiPathways | Endochondral Ossification | |||
Prolactin receptor signaling | ||||
Growth hormone receptor signaling | ||||
Adipogenesis | ||||
Synthesis, Secretion, and Deacylation of Ghrelin |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016005) | |||
REF 2 | Albutropin: a growth hormone-albumin fusion with improved pharmacokinetics and pharmacodynamics in rats and monkeys. Eur J Pharmacol. 2002 Dec 5;456(1-3):149-58. |
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