Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0XJ6C
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| Former ID |
DIB006185
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| Drug Name |
DIAPLASININ
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| Synonyms |
Diaplasinin < USAN; PAI-749; 1-Benzyl-3-pentyl-2-[6-(1H-tetrazol-5-ylmethoxy)naphthalen-2-yl]-1H-indole
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| Drug Type |
Small molecular drug
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| Indication | Thrombosis [ICD-11: DB61-GB90] | Phase 1 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C32H31N5O
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| Canonical SMILES |
CCCCCC1=C(N(C2=CC=CC=C21)CC3=CC=CC=C3)C4=CC5=C(C=C4)C=C(C=C5)OCC6=NNN=N6
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| InChI |
1S/C32H31N5O/c1-2-3-5-13-29-28-12-8-9-14-30(28)37(21-23-10-6-4-7-11-23)32(29)26-16-15-25-20-27(18-17-24(25)19-26)38-22-31-33-35-36-34-31/h4,6-12,14-20H,2-3,5,13,21-22H2,1H3,(H,33,34,35,36)
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| InChIKey |
BDPXZFKVHDEPIQ-UHFFFAOYSA-N
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| CAS Number |
CAS 481631-45-2
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effect of the small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor, PAI-749, in clinical models of fibrinolysis. J Thromb Haemost. 2010 Jun;8(6):1333-9. | |||
| REF 2 | Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res. 2012 Jan;40(Database issue):D1128-36. | |||
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