Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0X6KS
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| Former ID |
DNC007169
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| Drug Name |
N-[4-(3-amino-1H-indazol-4-yl)phenyl]benzamide
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| Synonyms |
CHEMBL223185; N-[4-(3-amino-1H-indazol-4-yl)phenyl]benzamide; N-(4-(3-amino-1H-indazol-4-yl)phenyl)benzamide; benzamide,n-[4-(3-amino-1h-indazol-4-yl)phenyl]-; BDBM50207504; ZINC35324132; 935660-76-7
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H16N4O
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| Canonical SMILES |
C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
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| InChI |
1S/C20H16N4O/c21-19-18-16(7-4-8-17(18)23-24-19)13-9-11-15(12-10-13)22-20(25)14-5-2-1-3-6-14/h1-12H,(H,22,25)(H3,21,23,24)
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| InChIKey |
ZBWAOEUPXWDTQS-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fms-like tyrosine kinase 3 (FLT-3) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Hematopoietic cell lineage | ||||
| Pathways in cancer | ||||
| Transcriptional misregulation in cancer | ||||
| Acute myeloid leukemia | ||||
| Central carbon metabolism in cancer | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based orally active multitargeted ... J Med Chem. 2007 Apr 5;50(7):1584-97. | |||
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